Government Contracts
For more than 20 years, ILS has provided exemplary research and laboratory services for various federal agencies and state governments. A listing of our current contracts is provided below:
National Institute of Environmental Health Sciences (NIEHS)
Support Contract for the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods
This contract promotes the development, validation, acceptance, and use of alternative and revised testing methods and strategies that shall be more predictive of human health and ecological effects than currently available methods and strategies, while replacing, reducing, and refining animal use. ILS has held this contract for over 10 years.
NTP and NIEHS Investigative Research Support
ILS conducts and manages multiple concurrent rodent (rats and mice) studies for NIEHS in order to better understand the genetic components of human disease and the impact of the environment on susceptible populations. These studies include animal dosing, in-life observations, necropsy, tissue collection, molecular analysis, in vitro assays, and reporting of results. ILS has provided these services under this contract for over 15 years.
Genetic Toxicity in Bacteria and Rodents
ILS performs genetic toxicity testing in rodents (rats and mice) and bacteria. This project consists of 4 overall Tasks. Task 1 is Induction of Micronuclei in Bone Marrow and Other Tissue. Task 2 is Testing for the Presence of Centromeres in Micronuclei. Task 3 is Induction of DNA Damage as Measured by the Single Cell Gel Assay, and Task 4 is Induction of Gene Mutations in Bacteria. ILS has provided maintenance and testing of rodents for micronucleus studies for over 10 years.
Environmental Polymorphisms Registry (EPR)
EPR is a study designed to collect and analyze blood samples from 20,000 individuals to test for genetic mutations that increase susceptibility to disease. ILS is currently managing the day-to-day aspects of clinical research, coordinating interactions between NIEHS Principal Investigators, and various collaborating investigators and staff; submitting materials for IRB approval and creating and managing study-specific databases.
Pathology Support for NIEHS
ILS provides necropsy, histology, histopathological interpretation, data acquisition into electronic format, gene expression, molecular pathology, immunohistochemistry, cell growth assays, and microarray pathology evaluation. ILS conducts Pathology Working Group reviews of pathology and toxicology data, target tissues, potential treatment-related lesions, and other selected tissues and lesions. ILS also provides support tasks for clinical research activities and data entry. ILS has had this contract for 10 years.
Support for Preparation of NTP Nomination Background Information and Documents
ILS prepares toxicological reviews of chemicals, chemical classes, and numerous non-chemical agents nominated to the NTP for testing. ILS staff conducts comprehensive online and manual literature searches on assigned agents, extracts information, and evaluates data to be included in these reviews. The reviews are used by the NIEHS Nomination Faculty and the Interagency Committee to Co-ordinate and Evaluate Chemicals in the selection and prioritization processes for identifying agents to be tested in the NTP.
Validation of a Human CD34+ Stem Cell Toxicity Bioassay (SBIR-Phase 1)
Environmental Protection Agency (EPA)
Envrionmental Services Assistance Team Region 4
ILS provides analytical, technical, and quality assurance support primarily to the EPA Superfund Program, other EPA programs, and Federal and State agencies. Services include identification, assessment, regulation, and remediation of environmental hazards which may pose a threat to human health or the environment. These services necessitate generating or gathering information on which to base administrative, regulatory, and/ or human health decisions.
Endocrine Disruptor Screening Program (EDSP) Lab Support (subcontractor to RTI International)
Analysis of Gene Polymorphisms
State of Georgia
Field Operations Support
ILS provides daily air quality monitoring services to identify potential airborne pathogenic threats as specified by Georgia DNR and the Department of Homeland Security. Samples are collected and delivered to health laboratories from a network of whole-air samplers in selected areas of Georgia.