Biomarkers & Kinetics
Proteins, Hormones, and Cytokine Analyses
Meso Scale Discovery® Platform; singleplex and multiplex, examples include:
- Metabolic Panel (Leptin, Insulin)
- Cardiac Panel (TnT, TnI, FABP3, Myo)
- Steroid Panel (Estradiol, Testosterone, DHEA, Progesterone)
- Proinflammatory Cytokines (Mouse/Human)
Western Blot
ELISA Development and Validation
- alpha 2u-globulin
Lead Scientist
Susan Borghoff, Ph.D., DABT
Phone: 919 281-1110 Ext. 717
Email: (JavaScript must be enabled to view this email address)
Dr. Borghoff joined ILS in 2006 as the Director of the Investigative Toxicology Division and oversees the Biomarkers and Kinetics program. She is an active member of the Society of Toxicology, and she was an Associate Editor for Toxicological Sciences (2003-2008) and served on the editorial board for Chemical Biological Interactions and Toxicology Letters. She has been a Diplomat of the American Board of Toxicology since 1994. Dr. Borghoff has served on review panels and as a working group member for national and international organizations including USEPA, NIEHS, NCI, IPCS, ECETOC, and IARC. In 1994, Dr. Borghoff received the Frank R. Blood Award for the best paper of the year published in one of the Society of Toxicology research journals. In 2000, she received the Society of Toxicology Risk Assessment Specialty Section Award. Dr. Borghoff has over 20 years of experience in study development, design, and management of in vitro and in vivo toxicological studies; she has a broad knowledge of pharmacokinetics and metabolism of specific chemicals as a step in studying the mode-of-action by which they induce a toxic and/or carcinogenic response. Dr. Borghoff received her Ph.D. and MSPH in Environmental Sciences and Engineering from the University of North Carolina at Chapel Hill.