Literature Search
ILS Literature Search integrates disparate sources of scientific information and translates them into actionable knowledge. We undertake a rigorous and systematic process that identifies and comprehensively summarizes relevant data in the literature from disparate sources and presents the results in a transparent and unbiased review. ILS’ customized search strategy identifies key studies and critical data needed to solve project-oriented problems, answer critical questions, and meet regulatory requirements.
Services
- Customize search methods and format reports to match your needs
- Integrate key studies and critical data from disparate sources, including peer-reviewed publications, patents and unpublished abstracts
- Draft toxicological reviews of agents that include background information, regulatory standards and toxicological data
- Prepare chemical information reviews that provide concise summaries of toxicological review and comply with regulatory guidelines (e.g., OECD, EFSA)
- Probe the toxicological profile of small molecules and natural products without incurring costs associated with chemical synthesis, wet lab experiments, and animal studies
- Improve understanding of mechanisms of toxicity and structure-activity-relationships
- Provide salient data and reviews to support risk assessments for public health and related applications
- Utilize broad scientific expertise and literature precedents to inform study design and assay development
Applications
- Integrate toxicity data from disparate sources, including peer-reviewed publications, patents and unpublished abstracts
- Reduce product development costs associated with chemical synthesis, wet lab experiments, and animal studies
- Support “go / no-go” decisions on a specific basis within the pharmaceutical, agriculture, chemical, and personal care sectors
- Verify the scientific credibility of review documents
- Leverage expert knowledge to save time and increase awareness of alternatives
- Meet regulatory requirements for chemical dossiers
- Improve understanding of mechanisms of action, including toxicity, efficacy, and structure-activity-relationships
Lead Scientist
Neepa Choksi, Ph.D.
As the Principal Investigator on the NTP Background Review Document Contract at ILS, Dr. Choksi is responsible for leading, managing, and reviewing preparation of technical and scientific review documents on a variety of environmental toxicants and natural products. She works closely with scientific and technical staff to ensure that all available literature and research has been identified and reviewed to ensure completeness. She has extensive experience in preparing scientific and technical information for a variety of audiences (public, governmental, scientific meetings). In addition to literature searching and reviewing expertise, Dr. Choksi has over four years of experience in evaluation of toxicological test methods as potential alternative test methods to currently used in vivo test methods. She also has knowledge of national and international chemical testing guidelines and regulations. Prior to her arrival at ILS, Dr. Choksi worked within the National Institute of Environmental Health Sciences to assist in science policy issues. She also has experience working with companies and individual inventors to develop patent applications for a variety of areas. Dr. Choksi received her B.S. in Chemistry from Bucknell University and her Ph.D. in Medicinal Chemistry from the University of North Carolina at Chapel Hill.