Information Sciences

ILS Information Science Program can assist in all stages of data acquisition, management and analysis. Our scientists have extensive experience in toxicology, chemistry, exposure risk assessment, molecular biology, alternative test methods and database development. We provide high level expertise in data procurement and assessment, database design, data management/visualization and scientific writing. Software tools are designed for comparative analysis of data from multiple studies across different endpoints.

Center for the Evaluation of Alternative Toxicological Methods Link to NICEATM

ILS provides the scientific and administrative support activities for the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), which in turn supports the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). The goal of ICCVAM is to promote the development, validation, acceptance, and use of alternative and revised testing methods and strategies that shall be more predictive of human health and ecological effects than currently available methods and strategies, while replacing, reducing, and refining animal use. ILS provides administrative support for the ICCVAM and its working groups; prescreens methods submitted for consideration by ICCVAM; coordinates the scientific peer review and interagency consideration of new test methods of multi-agency interest; convenes expert workshops to evaluate the validation status of new methods and to identify research and validation studies needed to fill critical knowledge gaps; and disseminates information on the current status of alternative test method development, validation, acceptance, and use. This work has included the creation and support of a website, development of ListServes, and other outreach activities. Report preparation and production are also critical activities on this contract.

Literature Search

Document Preparation

Database Development

Geographical Information Systems

Lead Scientist

David Allen, Ph.D.

As the VP of Science and Strategy at ILS, Dr. Allen provides scientific leadership, management, and direction to ILS’ programs and core services. He works closely with all scientific staff to support the planning and execution of ILS growth plans, and leads staff planning and employee development. Dr. Allen has over 15 years of experience in regulatory toxicology, test method validation, and in vitro biology. At ILS, Dr. Allen has spent over 8 years providing contract support and leadership for the National Toxicology Program’s Center for the Evaluation of Alternative Toxicological Methods (NICEATM). Prior to joining ILS, he was a toxicologist for the Food and Drug Administration, Center for Drug Evaluation and Research, where he was responsible for evaluating toxicological and pharmacological data for investigational new drug applications. Dr. Allen received his B.S. in Zoology from North Carolina State University, his M.S. in Biological Sciences from the University of North Carolina at Wilmington, and his Ph.D. in Cell Biology also from North Carolina State University.